Omega-3 Polyunsaturated Fatty Acids in Prevention of Mood and Anxiety Disorders

Omega-3 Polyunsaturated Fatty Acids in Prevention of Mood and Anxiety Disorders

Summary

Nutrition is a modifiable environmental factor that might be important in prevention medicine. Omega-3 PUFAs are well tolerated and accepted, and have been applied for many years as the secondary prevention in various chronic medical diseases and mental disorders. 

In this review, we found that the clinical evidence about omega-3 PUFAs’ preventive benefits on mood and anxiety disorders is supported by their regulatory effects on immunomodulation, anti-inflammation, signal transduction, neurotransmission and neuroprotection. 

Our current review calls for more prospective clinical trials in identified high-risk populations to justify the preventive application of omega-3 PUFAs in daily practice.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540034/