Scientists sometimes use bed rest studies to simulate spaceflight because lying down eliminates the head-to-foot gradient that places a load on the heart. But Prof Levine said water immersion for long periods in a horizontal position is an even better model for time spent in orbit.
Information source:
BBC News - Long spaceflights and endurance swimming can 'shrink the heart'
https://www.bbc.co.uk/news/science-environment-56559494
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