Sunday, March 2, 2014

The intake of antioxidant flavonoids (commonly available in oranges, apples and berries) reduces the risk of dementia.

The intake of antioxidant flavonoids is inversely related to the risk of incident dementia.

Info source: an article in http://www.ncbi.nlm.nih.gov/m/pubmed/10959944/

We reproduce the article here for your convenience.

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Intake  of flavonoids and risk of dementia.
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AuthorsCommenges D, et al. Show all Journal
Eur J Epidemiol. 2000 Apr;16(4):357-63.

Abstract
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It has been postulated that oxidative stress may play a key role in dementia. This is substantiated by the recent discovery of the protective effect of wine. In wine, the flavonoids--powerful antioxidant substances also contained in tea, fruits and vegetables--have been thought to offer such protection. We investigated whether flavonoid intake could be associated with a lower incidence of dementia in a cohort of 1367 subjects above 65 years of age (Paquid). A questionnaire was used to evaluate their intake of flavonoids and subjects were followed-up for 5 years between 1991 and 1996: 66 incident cases of dementia were observed. We estimated the relative risk (RR) of dementia according to tertiles of flavonoid intake using a Cox model. The age-adjusted RR of dementia was 0.55 for the two highest tertiles compared to the lowest (95% CI: 0.34-0.90; p = 0.02). After additional adjustment for gender, education, weight and vitamin C intake, the RR was 0.49 (95% CI: 0.26-0.92; p = 0.04). 

We conclude that the intake of antioxidant flavonoids is inversely related to the risk of incident dementia.

PMID 10959944 [PubMed - indexed for MEDLINE]

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