*In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function*
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126018/
Conclusion:
While it is recognized that a
dietary supply of macronutrients is essential for human health, micronutrients such as vitamins and trace minerals are also crucial for maintaining brain health. In contrast, deficiency or disturbances in any of these can be associated with brain dysfunction and contribute, at least in part, to the pathophysiology of several neurological disorders. On the other hand, interventions designed to optimize the levels of such macro and micronutrients can potentially form the basis for therapeutic strategies aimed at improving cognitive functioning, particularly in the aging brain (Figure 3). Moreover, diet and nutritional status are the most critical modifiable factors regulating the gut microbiota at different time points across the lifespan and under various health conditions. Therefore, advances in our understanding of the mechanisms underlying the actions of macro and micronutrients on the brain and the microbiota-gut-brain axis will facilitate the development of nutritional interventions aimed at optimizing brain function and preventing or treating neurodegenerative disorders and other age-related conditions.
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