Vitamin
B12 is involved in the metabolism of all cells in the body; but the effects of
deficiencies are first seen in the blood and then
the nervous system. An anemia, called megaloblastic anemia, because it
is characterized by large red blood cells, is a common manifestation of
deficiency. The low red blood cell count is very well tolerated by the patient
even when severe, and is always cured by the taking of small amounts of B12.
Mild problems with the nervous system characterized by numbness
and tingling in the hands and feet also develop. These sensations are
reversible in early stages; however, damage to the nervous system can become
much more severe and irreversible after prolonged deficiency.
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