http://www.sciencedirect.com/science/article/pii/S0165017306000178
Quote:
"Calorie restriction regimens and calorie restriction-mimetics trigger sirtuins in a wide variety of organisms, ranging from bacteria to mouse.
In a mouse model of Huntington's disease, resveratrol-induced SIRT1 was found to protect neurons against ployQ toxicity and in Wallerian degeneration slow mice, resveratrol was found to protect the degeneration of neurons from axotomy,
Suggesting that resveratrol may possess therapeutic value to neuronal degeneration.
This paper mainly focuses on the role of resveratrol in modulating AD pathomechanisms."
Unquote.
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